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"Based on published estimates, a 10percentt reduction in regulatory review time reduces the total investment required to develop a new medication by over $12 million," Dr. McClellan said in the speech.
Based on published estimates, we derive the optimal prices for three measures of quality that have been incentivised in the English National Health Service since April 2010 (treatment in an acute stroke unit, rapid brain imaging, and thrombolysis with alteplase).
For cases requiring medical care, age-specific costs for mild and typical pertussis cases were calculated based on published estimates [20], [33], [34] updated to 2006 levels using the US price index for medical care (available at www.bls.gov).gov
The numbers of segregating sites were fixed at the values obtained from the re-sequencing data, the population recombination rate parameter rho ( = 4Nr, where N is the population effective size and r the recombination rate between adjacent sites per generation) was assumed to be 0.24, based on published estimates [73] using the HapMap data for the genomic segment spanning the NAT2 gene.
Model parameters were based on published estimates.
Secondary age constraints based on published estimates of divergence times were not used.
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These exposure estimates were based on published exposure estimates in the same industries (IARC 1984; Lindstedt and Sollenberg 1982) and other published epidemiologic studies.
These particles were added in an elliptic footprint centered at an interpolated position between recorded locations and with a semi-minor axis (longitudinally) of ∼111 km (1°) and a semi-major axis (latitudinally) of ∼889 km (8°), based on published range estimates of accuracy for light-based geolocation data [13], [20].
Nudds and Dyke had assumed a weight of 250 grams for the Munich specimen Archaeopteryx, a young juvenile, based on published weight estimates of larger specimens.
The cost per adverse event is based on published Italian cost estimates and have been applied to all relevant erlotinib or docetaxel serious adverse events (≥grade 3) as per Table 3.
The review - based on published data - estimated at least 800,000 older people were going without vital help.
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based on published sequences
based on published reports
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based on published meta-analyses
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based on published results
based on published values
based on published descriptions
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based on available estimates
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