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Another transgenic strain combining mutant APP, PSEN2 and tau (tripleAD) was analyzed with a particular focus on mitochondrial function, based on proteomic data that were obtained in these mice showing that one-third of deregulated proteins were mitochondrial.
The group used computational knockouts of network proteins, validation experiments with RNAi, and model revision based on proteomic data, to predict the effects of combined inhibition of ERBB2 and c-MYC or EGFR.
This may open the door to peakcoding projects based on proteomic data, thus offering an alternative to DNA barcoding analyses.
Based on proteomic data from 5 to 12 months both NRF1 and PGC1A are predicted to be inhibited.
Based on proteomic data across 28 microbial community samples, G-plasma constituted about 9.0 ± 4.9 % of the community [ 37].
When assaying fasting regulated hepatic mRNAs and proteins to KEGG pathways, nine pathways were selected solely for old obese animals based on proteomic data; in turn, corresponding mRNAs were annotated to twice as more differentially regulated pathways in young and old mice, both lean and obese (Table S 10).
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Tfu_v3: The third version of the model generated in this study (Tfu_v3) is based on proteomic experimental data generated by our group in collaboration with the Manitoba Centre for Proteomics & Systems Biology, the University of Manitoba.
The expression of Pf-AdT subunit A is predicted in all life cycle stages of parasite based on proteomic and microarray data.
This will clearly improve data mining to understand biological phenomena based on proteomic investigations.
Such changes can be identified by pharmacoproteomics approach based on proteomic technologies.
Based on proteomic prediction tools (Sosui, DAS, TMPRED, TOPPRED), E4orf4 may contain a hydrophobic patch that creates an amphipathic helix.
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based on morphological data
based on proteomic analyses
based on clear data
based on fragmentary data
based on proteomic assays
based on proteomic patterns
based on proteomic technologies
based on proteomic studies
based on proteomic investigations
based on false data
based on proteomic applications
based on genetic data
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