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In this paper we describe a highly efficient strategy, based on proteomic analysis and elution chromatography, by which a protein of interest may be isolated from copurifying contaminants.
Xu et al. (2008) reported that accumulation of proteins associated with the TCA cycle increased during 6 10 DAF (in the early storage phase), based on proteomic analysis of developing rice kernels.
Several nutrient acquisition-related proteins coded by GI-associated genes were found to be comparatively abundant based on proteomic analysis (supplementary table S1, Supplementary Material online).
Recently, our group suggested that the mitochondrial isoform of the gluconeogenesis-related enzyme phosphoenolpyruvate carboxykinase (gi | 1709734) is a promising drug target based on proteomic analysis.
Based on proteomic analysis, the proteins secreted by HepG2 cells that have been treated with benzyl butyl phthalate (BBP) are associated with DNA damage, tumor progression, apoptosis, energy metabolism, and cell structure and motility [ 6].
It has been previously suggested based on proteomic analysis of high MAB productivity in NS0 cells, that up-regulation of processes such as energy metabolism may be involved in the improved production of MAB [ 31].
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In summary we assembled a global pathway model for AKI based on proteomic changes, and further support the concept that the approach of in-depth Systems Biology coupled with high-resolution proteomic analysis represents a valuable approach to elucidate complex pathways and systems, especially in multifaceted diseases such as AKI.
This will clearly improve data mining to understand biological phenomena based on proteomic investigations.
Such changes can be identified by pharmacoproteomics approach based on proteomic technologies.
They are known to be present in cysts based on proteomic or transcriptomic analyses.
We also incorporated published annotation corrections based on proteomic evidence [ 71, 72].
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