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Based on prior models as well as the proteolysis and SAXS experiments, we constructed several mutant semisynthetic PTENs to investigate possible PTEN residues that contribute to the closed conformation of 4p-PTEN.
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The delivery time was based on prior animal model studies indicating the efficacy of short duration of IACFM applications [ 16- 18].
To date, however, an integrated approach, one combining the use of physicochemical model construction based on prior research and model verification via construction of corresponding reaction systems using purified proteins, has not been extended to understand APC regulation of the prothrombinase complex stability and function.
This study proposed and verified a PACS success model from a socio-technical perspective based on prior IS success models.
Character mapping methods are based on prior distributions and models of evolution, the reliability of which remains unclear [ 29].
We included covariates in the linear multiple regression model based on prior decisions, but in the final models covariates with a value of p > 0.7 were excluded.
We chose changes in PANSS item scores obtained at Weeks 1 and 2 as input variables based on prior work with prediction models.
Pattern recognition with a statistical model based on prior information has been used for modeling such decision making.
If only the FAO_MOD texture-class information is available, the recommendation changes to the FAO_MOD + T/S_MS_HCC model based on prior development of the FAO_MOD + T/S_MS_MRC model.
In prediction risk modelling, AFP only allowed for a small increase in DR when added to the prior risk model, as well as to the model based on prior risk, PAPP-A and f β-hCG.
The approach makes it possible to 1) quantify uncertainty about the relative importance of data features and 2) impose constraints on the obtained models based on prior neuroscientific knowledge.
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