Sentence examples for based on primary sequence from inspiring English sources

As one might expect, gene family partitions are more inclusive than those based on primary sequence, and hence more conservative in identifying single-gene families [ 40].

The secondary structural elements of V4 and V7 of the myxozoan 18S rRNAs were found to be highly informative and revealed evolutionary trends of various regions of the gene hitherto unknown, since previous analyses have been based on primary sequence data excluding these regions.

When factoring in the size of GFP, Q145 is 1.4 fold larger than the Q23 construct based on primary sequence.

Compared to the traditional phylogenomic approaches based on primary sequence, our strategy only makes use of gene relationships so as to be immune to system errors caused by compositional bias, within-site rate variation and so on.

Searching for U-snRNA candidates from Giardia based on primary sequence similarity failed, as expected, due to the observed low sequence similarity between Giardia and other well studied eukaryotes.

An impediment to understanding this process is the fact that FIT proteins do not share homology to known proteins or protein domains, making it difficult to infer a mechanism based on primary sequence.

As the field expands, and focus shifts to inferring 3D structures based on primary sequences and data obtained from other types of structural experiments, I see tremendous opportunities for young scientists with various expertise in the physical sciences.

In this section, we employed the support vector regression approach to quantify the sequence-RD relationship and predict the RD values based on primary sequences information only.

Identification of CAZyme catalytic activity based on primary protein sequence is difficult, nevertheless, detailed comparisons with previously characterized enzymes has allowed us to determine likely enzyme activities and targeted substrates for many of the P. parasitica CWDEs.

We developed an alignment-based method that allows to quantify the similarity of ncRNAs solely based on primary deep sequencing data by considering the position and length-dependent patterns of reads aligned to short intervals on the genome.

Primers flanking the gap region were designed based on primary transcript sequences (Additional file 4).