Sentence examples for based on primary mutations from inspiring English sources

Mostly the diagnosis is based on primary mutations for diseases like LHON, Leigh's disease, NARP, MELAS etc.

Also, it has to be emphasized that current large screening initiatives based on primary airway cells are not able to target rare CF mutations, since explanted lung tissue homozygous for rare mutations is generally not available.

Importantly, current screening efforts based on primary airway cells or intestinal organoids cannot specifically target single rare CFTR mutations or mimic multiple cell types.

Based on primary and secondary structure comparisons, this helix in Vps1 is well conserved making selection of charge-switch mutations straightforward.

completing p group division based on primary division.

Studies based on primary data would bring very intuitive results.

Data collection was based on primary and secondary sources.

The sample size was based on primary efficacy analyses.

Based on these mutations, we could infer both the primary limiting stress that the pathway placed on its host as well as the biochemical mechanisms that the cells used to overcome this stress.

We found no differences in the clinicopathologic factors of the antecedent primary melanoma based on the mutation status, similar to prior studies (Shinozaki et al, 2004; Edlundh-Rose et al, 2006), but in contrast to one study which reported association between BRAF positivity and thinner primaries with lower numbers of mitoses (Devitt et al, 2011b).

With respect to the classification method, we implemented a one-versus-all multiclass classification schema to identify the primary tumor site based on patients' mutation-associated features and the gene pathway feature.