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There was a maximum of 108 questions, with skip logic included to direct responders away from questions that were not applicable to them based on previous responses.
Due to likely variations from year to year, data on human factors and resource utilization will be collected on an annual basis using electronic tools (such as recurring auto-filled surveys based on previous responses so as to only report changes), and while the data may not capture variation in the daily activity levels or acuity in the unit, this will represent the average condition.
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This probability and the hemodynamic data are then modified based on previous patient responses to fluid administration and deviations from the model predictions.
With this approach, the researcher continually refined and modified interview questions based on previous participant responses and explored themes as they emerged from interviews [ 15].
The dose of caspase inhibitors was based on previous dose-response studies [66], [67].
Based on previous dose-response investigations, the mycobacterial antigens were all used at 1 µg/ml.
Based on previous experiences, response rates among patients were expected to be slightly higher.
Based on previous dose-response experiments, 150 μg/kg liposomal siRNA every 72 hours effectively downregulates gene expression in vivo.
Based on previous specialist response rates to the 2004 Canadian National Physician survey, we expected to approach 4 physicians for every physician we needed to recruit[ 5].
These optimal LPA and S1P concentrations were determined based on previous dose-response curves in hNP cells (Hurst et al., 2008b).
We chose a 10 ng/ml dose of IL-7 for further experiments, based on previous dose-response studies conducted in other cell types that found that 10 ng/ml was required for stimulation of mononuclear and T-cell proliferation [ 11, 13] and TNF-α production [ 12].
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