Indeed, BARD's timeliness increased by nearly one hour and based on previous estimates [ 12] that a delay of one hour in detection results in as much as $250 million additional economic costs, this increase is quite significant.
Based on previous estimates by the company, the relief well would be completed no sooner than early August, barring and further setbacks.
Since our region of interest lies tailward from the current sheet hinging area, the parameter α was fixed at a constant value of α=3 based on previous estimates in TF04.
The neutral rate estimate for species in our alignment, based on previous estimates from other genomic loci [18], [19], is 2.75 substitutions/site.
Antigen-specific fixed values of rho, ρ, the sero-reversion rate, were fixed based on previous estimates from Tanzania [24](for MSP-119 rho = 0.0173/yr & AMA-1 rho = 0.0262/yr).
Therefore, based on previous estimates on the differences among substitution rates for the species considered here [22] [25], we repeated our analysis of population dynamics using dates of integration based on rates of 5.94×10−9 s/s/y for CERV-K and 6.93×10−9 s/s/y for RhERV-K (with human still at 3.3×10−9 s/s/y).
Based on previous estimates in the area, a LBW prevalence of 20% and an estimated 25% reduction to 15% in the presence of ITNs [14], 411 women per group were needed to show a lack of difference between the two groups with a confidence interval of 7 (8% to 22%), at the 5% level of significance with a 80% statistical power.
The prior on Ttrans is based on previous estimates [ 6, 8] and its standard deviation allows for a broad range.
These associations would not be expected, based on previous estimates of near-background levels of radiation exposure following the accident.
Based on previous estimates of HIV, HSV-2 and syphilis prevalence in the area, HIV prevalence was the lowest, so the sample size was based on that estimate.
