Plackett Burman design was first used to screen significant factors from the seven variables including sucrose, yeast extract, sodium citrate, sodium acetate, NH4H2PO4, MgSO4, and MnSO4, based on preliminary experiments and related reports.
But it was taken as a deeply troubling sign among drug policy experts who believe the F.D.A. has been far too influenced by patient advocates and drug companies, and has allowed the delicate balance in drug approvals to tilt toward speedy decisions based on preliminary data and away from more conclusive evidence of effectiveness and safety.
The concentrations of adiponectin and MAPK inhibitors used in the experiments were based on preliminary experiments and studies previously carried out in our laboratory [ 30- 32].
Therefore, choices of parameters in this work are based on preliminary testing and summary statistics from the distance distribution between the query vector and all vectors in the database.
However, these model based approaches usually focus on detailed design and less on conceptual design where key decisions are made based on preliminary analysis and usually little available information.
A United Nations spokeswoman said the number of dead was based on preliminary reports and could change.
A Sunoco spokesman, Gerald Davis, said in an interview that "based on preliminary studies and under the current economic conditions, it would be feasible" to dredge.
We selected BeF2-containing salts as the possible candidates based on preliminary economic and thermal hydraulic consideration.
He noted that the analysis was based on preliminary data and that the highest-income Americans were more likely than others to file their returns late, so his data might understate the growth in inequality.
Hylton's focus on pitot-tube icing as the most likely reason behind the loss of Air France Flight 447 may well be correct, but seasoned accident investigators know not to speculate based on preliminary information and similarities with past events.
