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Similarly, SOP models allow the implementation of a proactive spectrum mobility strategy based on predicted occupancy patterns which avoids collisions with incumbent primary users [5, 6].
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Given the importance of the hematopoietic transcription factor TAL1 for erythroid gene activation, we predicted candidate enhancers based on genomic occupancy by TAL1 and measured their activity.
Our examination of TAL1 OSs showed that predicting enhancers based on occupancy by a single critical TF was quite accurate, giving a success rate of 56% in transient transfections of hematopoietic cells and 65% in transient transgenic mice.
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