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Identified phosphoproteins mainly fell into three categories based on predicted function: proteins involved in cellular communication, transcriptional regulation and cellular structure.
The data identified a variety of differentially expressed genes that have been organized into metabolic clusters based on predicted function and expression patterns.
The genome of Pa comprises a single circular chromosome of 5,064,808 bp (GenBank accession number AC FM162591) with a total of 4,403 predicted protein-encoding open reading frames which can be classified based on predicted function.
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These were then grouped under several categories based on predicted functions (Table 1).
EST-derived markers were developed after selecting a number of genes based on predicted functions and gene ontologies and revealing molecular polymorphisms through SSCP analysis or minisequencing, as described in [ 39].
We selected 24 genes for analysis based on predicted molecular function and on relative abundance of sequencing reads.
A Functional Catalogue (FUNCAT) analysis of the transcripts in each subset (Always, Never, Specific and Non-specific) was carried out based on predicted protein function.
GO-Slim classification also identified groups of genes based on predicted molecular functions; again the largest group of genes (37.5%) belonged to the 'unknown molecular function' category followed by 'other enzyme activity' (16.5%), hydrolase activity and other binding activity.
An initial list of biochemical reactions was assembled based on predicted enzymatic functions in the genomic annotations available from IMG, UniProt, and KEGG [ 23- 27].
Only 7.8% of Mexico City children had abnormal lung function tests based on predicted values.
Abnormal lung function tests based on predicted values are seen in 7.8% of MCMA children.
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