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Additionally, the value of peptidomimetic modification and alterations based on posttranslational modifications for the design of APLs was examined.
Here enrichment methods could be applied that are based on posttranslational modifications of secreted proteins, for example, glycosylation [ 124].
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It is based on the posttranslational modification of proteins by the ligation of ubiquitin, a 76 amino acid signaling peptide that is conserved across eukaryotes.
Our research has focused on posttranslational modifications which can occur on YY1 in a cell cycle dependent manner.
The localization and activity of Ras proteins are highly dependent on posttranslational modifications at their C-termini.
The induction of p53 transcriptional activity depends mainly on posttranslational modifications together with protein/protein interaction [2].
The ability of α-dystroglycan to function as a receptor relies on posttranslational modifications, especially glycosylation.
p53 transcriptional activity depends mainly on posttranslational modifications and protein/protein interaction.
Chromatin structure depends to a great extent on posttranslational modifications of histones.
The presence of a specific interaction might depend on posttranslational modifications and on the analyzed cell type.
HDAC inhibitors are being considered for the therapy of melanoma despite limited data available on posttranslational modifications of histones.
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