The pooled ORs based on pools of studies with consistency among the definitions for OA inclusion, OA progression, and the determinant under study, were 2.38 for knee pain at baseline (95% CI,1.74 3.27; I = 52%) (Fig. 1) and 2.66 for the presence of Heberden nodes (95% CI, 1.46 8.84); I = 0%) (Fig. 2).
Having once owned a company called Mojo Softheads, which wrote and marketed the finance industry's standard software for structuring bonds based on pools of mortgages (yes, you may have heard of the unhappy consequences of this process), I can empathize with a firm's desire to protect its proprietary materials.
CDOs (securitisations of securitisations, which are instruments based on pools of mortgage-backed securities) and SIVs (which issue shorter-term debt than for most CDOs) caused big problems because they were very opaque and particularly susceptible to correlation and liquidity risk.Fortunately, life need not be so complicated.
Fibrin was first used as a sealant based on pools of commercial fibrinogen.
In fact, the commercial IGRAs and TST use a greater variety of epitopes to elicit M. tuberculosis immune responses by effector memory T-cells [28] [29] being TST a crude preparation of several mycobacterial antigens, and commercially IGRAs based on pools of overlapping peptides spanning the whole length of CFP-10 and ESAT-6 proteins [5].
In fact, QFT-IT uses a greater variety of epitopes to elicit M. tuberculosis immune responses by effector memory T-cells and is based on pools of overlapping peptides spanning the whole length of CFP-10 and ESAT-6 proteins and an additional peptide from RD11 [4], [4].
A meta-analysis of these studies would provide a useful dose-response gradient curve based on pooling of the results of known studies to date.
We examined the association between use of NSAIDs and lung cancer risk based on pooling of data from two studies.
This comparison must be treated with caution as the non-SDQ effect sizes are based on pooling of results from a wide variety of measures of EBD.
The safety analysis was based on pooling of events from data available on all doses identified in the evidence base for each treatment because of the low frequency of observed events.
Additionally, because the isoform annotation is based on pooling of reads from 27 samples, the distribution of this splice isoforms amongst the individual samples is not apparent in the current study.
