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We designed sets of RCA padlock probes based on polymorphisms in the elongation factor 1-α (EF-1α) gene to detect the dominant FHB species, comprising lineages of the Fusarium graminearum species complex (FGSC).
In addition, this method was compared to an in-house multilocus sequence typing (MLST) method based on polymorphisms in three housekeeping genes, the rrs locus and two envelope proteins.
The current study was conducted to explore the role of two-way epistatic interaction effects on the plasma levels of the t-PA and PAI-1 proteins based on polymorphisms in genes from the renin-angiotensin and fibrinolytic pathways in a large-scale population-based sample from urban West Africa, and to assess whether such analyses are significantly more informative than single SNP analyses.
Subtypes are defined based on polymorphisms in region J of the same combination of mec and ccr complexes [ 8].
Microbial diagnostic microarrays for the detection of pathogenic E. coli were designed based on polymorphisms in single genes [ 10, 11] or on libraries of virulence determinants [ 12- 14].
With multilocus sequence typing, meningococcal isolates are classified into different sequence types based on polymorphisms in seven housekeeping genes considered not to be under selective pressure.
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Finally spoligotyping (spacer oligonucleotide typing) based on polymorphism in the chromosomal direct repeat (DR) locus is often used as a fast screening method [ 7].
Cytotoxin-associated gene A (CagA) is a cytotoxin-associated protein, linked with peptic ulcer and gastric cancer [ 6]. H. pylori strains can be grouped as Western and East-Asian subtypes based on polymorphism in 3′ repeat region of the cagA gene, which results in the variation of clinical outcome in East-Asian and Western countries.
Common marker in this study refers to markers based on polymorphisms found in the orthologous sequences between and lily and tulip (although the specific polymorphism may differ between the two species), and thus their mapping position can be used to study synteny between the two species.
Sequence-tagged site (STS) markers for candidate genes were designed based on polymorphisms detected in the parents.
All the aforementioned results for the 17-kb region encompassing age-1 its neighbors are based on polymorphisms collected in the coding and intronic sequences of these genes.
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