Sentence examples for based on polygenic profiling from inspiring English sources
The present study provides a novel perspective on endurance genetics based on polygenic profiling in the Gorkha population.
Individual risk prediction and stratification based on polygenic profiling may be useful in disease prevention.
Several studies have shown that risk-profiles based on the known common susceptibility alleles have limited discrimination for breast cancer (Gail, 2008; Pharoah et al, 2008; Wacholder et al, 2010) and for prostate cancer (Salinas et al, 2009), leading some investigators to conclude that the clinical utility of risk prediction based on polygenic profiling is still limited.
The genetic architecture of schizophrenia is based on polygenic trajectories.
Apart from this, family studies have provided evidence that there is a genetic predisposition to DDH based on polygenic-multifactorial inheritance [ 7].
It is not discrimination based on racial profiling.
The second direction involves dug screening based on cytological profiling.
This association study was based on logistic polygenic models, one with separately taken single nucleotide polymorphisms and the other with haplotypes as fixed effects.
Robust methodology has been developed to account for genetic background, based on a polygenic model and which is implemented in the GRAMMAR-CG approach used in the analysis presented here.
Thus, genomic pre-selection (GPS) leads to biased EBV and reduced accuracy in national genetic evaluations based on a polygenic model [ 10].
