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Patients were analysed based on polyamine intake, with the highest (75 100%) quartile group vs a group including quartiles 1 3 (0–25 505–50 and 50 75%).
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Considering the design of novel antiparasitic drugs based on polyamine compounds and amino alcohol derivatives, lipophilicity is an important parameter.
Also, it must be acknowledged that the original clinical trial design did not include prospective stratification based on dietary polyamine intake.
For example, another oxidative pathway leading to NO generation based on polyamines has been described (Tun et al. 2006).
This information was combined with the frequency of intake reported by the women and daily intake based on daily recommended intake stated on the supplement.
If participants were missing intake data at one of the follow-up examinations, the mean intake was based on the available intake data.
Transformation was based on Ig10 (alcohol intake +1), where alcohol intake resembles current or lifetime beverage specific or total alcohol intake, respectively.
The test for trend across categories of intake was based on the mean intake within each group.
The poverty estimates are derived from the household consumption expenditure data based on calories intake.
Dietary analyses were based on mean intake per individual.
Intake quartiles for fish and ω-3 fatty acids were categorized based on the intake values of control group.
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