Sentence examples for based on point mutations from inspiring English sources

ClonalFrame determines the genetic relationships of bacteria based on point mutations and homologous recombination [35].

These 'bi-stable' channelrhodopsins are based on point mutations at the C128 position and elicit long-lasting photocurrents that can be switched off by a green light pulse [6].

The most frequently acquired resistance to flucytosine is based on point mutations in the FUR1 gene.

Leukocyte adhesion deficiency type 1 (LAD-1) is an autosomal recessive disorder based on point mutations within the β2 integrin, resulting in either its absence on the cell surface or the inability to associate with the corresponding α subunit.

One such method, based on point mutations alone, has previously been described [ 11], yet our method, using the same data, performed better on the subset of samples for which we were able to compare the two methods.

Thus, we evaluated classifiers based on somatic point mutations only, here used as a collective term for single nucleotide substitutions, short insertions and deletions, and classifiers based on point mutations as well as SCNAs, separately.

This method is designed based on point mutation at the hot spot region in target drug-resistant gene using LAMP-polymerase chain reaction (PCR), hybridization, and thermal melting for differentiating homoduplex DNA (drug-susceptible stain) and heteroduplex DNA (resistance mutant).

Point mutation however cannot be the main force driving genome growth, because it does not give rise to gene duplication [3] [8], and because the pace of evolution based on point mutation alone would be too slow.

Nevertheless this early classification, based entirely on point mutations, was compiled only from two mutation tests; thus, relying on EST sequencing data, it was still not reliable according to our model which incorporated an additional mutation mode.

For this calculation, gaps were treated as missing data, so the differences between sequences were based only on point mutations (nucleotide substitutions).

Exchange groups cluster AAs based on accepted point mutations to represent conservative replacements through revolution.