Sentence examples for based on physicochemical parameters from inspiring English sources
Briefly, the structure-based druggability assessment identifies all cavities on a given three-dimensional structure and assesses their likely druggability based on physicochemical parameters that are independent of the homology of the protein to known drug targets.
Almost all methods have shown overall accuracies higher than 85% instead of 80.8% for models based on physicochemical parameters.
Based on physicochemical parameters, such as particle size and zeta potential, a schematic model for the potential interaction of the drug with the delivery agent was developed.
Unfortunately, although the microbial pathways involved in N2O formation have been well documented, most of the established statistical models for estimating N2O emissions were currently still limited based on physicochemical parameters but without taking the microbial traits into consideration (Hu et al. 2015).
In T. thermophila the gene ymf64 has been identified as a putative ribosomal protein, based on physicochemical parameters of the predicted protein [ 3].
In the universal region, three predicted B-cell epitopes, No. 3 (CRRKNYG: N-1186-1192-C), No. 4 (YPTYHTH: N-1209-1215-C), aNo.No. 5 (STDRSPY: N-1223-1229-C), highhigh scores in an evaluation based on physicochemical parameters including hydrophilicity, polarity, accessibility and flexibility (Fig. 1b).
Therefore, a great effort has been devoted to the biomonitoring of OA in the marine environment during the last two decades, mainly based on physicochemical and physiological parameters using mussels as sentinel organisms.
These two cases fit with the argument based on physicochemical properties and four-column code as well.
based on physicochemical and 3D similarity studies.
Can we control assembly and disassembly using modulators based on physicochemical principles?
Results show that our kinase scoring function, based on physicochemical descriptors, successfully generates kinase-focused libraries.
