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This nonlinear rheological behavior can be seen in gels based on physical interaction (e.g., hydrogen bond, ionic interaction, and entanglement of polymeric chain).
714 flavivirus-associated mosquito proteins were inferred from three data sources based on physical interaction assays, genome-wide RNAi screens and microarray results.
Using three datasets based on physical interaction assays, genome-wide RNA interference (RNAi) screens and microarray assays, we identified 714 putative DENV-associated mosquito proteins.
The majority (51%) of proteins in the network is at least partially projected/included based on physical interaction which favors evolutionary conserved processes and hence explains the enrichment in core cellular processes.
The distribution of pathway size in our study is statistically consistent with that of pathways generated from two previous methods (Kelley and Ideker, 2005; Ulitsky and Shamir, 2007) based on physical interaction data and GI data with the P-value of 0.04 and 2.4 × 10−5, respectively, by the Wilcoxon Rank Sum test (Fig. 2).
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To make inferences about our network-based hypothesis, we used two different mappings: one based on physical interactions, and another based on mRNA correlations.
A protein interaction network was constructed between candidate genes and cyclins, using the software Cytoprophet [ 35], based on physical interactions between known protein domains in the Pfam domain database, database of interacting proteins [ 48] and protein databank [ 49].
The hydrolytic degradation of monodisperse lactic acid oligomers was studied in vitro to gain insight into the degradation of oligolactic acid grafted to dextran, which we use for the preparation of hydrogels based on physical interactions, or the degradation of PLA/PLGA.
We next performed an analogous analysis based on physical interactions.
We excluded data based on synthetic lethal and dosage lethal interactions because they are not necessarily based on physical interactions and have not been systematically determined.
Additionally, hydrogels that (dis)assemble based on physical interactions offer shorter-term dynamic control of cell microenvironment structure or chemistry.
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based on physical layer
based on physical proximity
based on physical condition
based on electrostatic interaction
based on physical appearance
based on physical distance
based on physical evidence
based on physical scale
based on constant interaction
based on robust interaction
based on physical hardware
based on physical modelling
based on electric interaction
based on physical examination
based on physical force
based on spatial interaction
based on electromechanical interaction
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