After alignment to the respective HLA gene reference sequence (hg19), two HLA gene haplotype sequences based on phase-defined SNVs were generated.
The nucleotide alignment was generated based on the protein alignment using codon alignment.
This alignment was then fitted to a second alignment based on a needle alignment of E. coli Slt70 and the RvhB1 protein from Brucella suis [116].
As a consequence we developed a novel registration algorithm which is based on an alignment of square subimages on the phase contrast images (Raza et al., 2012).
The alignment size and RMSD based on this virtual alignment are termed the "virtual alignment size" and "virtual RMSD (vRMSD)", respectively.
To this end, we first define the local kernel alignment based on centralized kernel alignment.
This alignment is based on the Multiz alignment algorithm [ 17].
We're providing a similar kind of service that's not based on algorithms, but is based on the alignment of the planets and the stars". .
A neighbor-joining tree was constructed based on the alignment.
An ortholog table was constructed based on the alignment results.
