Sentence examples for based on persistence only from inspiring English sources
Under-predictions as NC were actually only observed for a small proportion of the simulated chemicals that were classified based on persistence only (0.1%% or 13/10,000) (Table 10).
In this analysis, the chemicals were grouped according to their UN GHS/EU CLP classification and classification driver, e.g. the rabbits of all chemicals that were classified based on persistence only were pooled together (De Wever et al. 2012; Barroso et al. 2013).
It is important to note, however, that for the NCD, about 25%% (50/198) of the animals tested with chemicals that were classified Cat 1 based on persistence only have both mean CO and mean IR scores less than 1 (Fig. 1).
On the other hand, the proportion of chemicals that were classified Cat 1 based on persistence only was 65.1 % in the NCD (52.7 % with CO persistence and 12.4 % with only CR, CC and/or IR persistence) and 35.5 % in the RCD (25.8 % with CO persistence and 9.7 % with only CR, CC and/or IR persistence).
A similar analysis performed on data of 723 rabbits tested in 181 studies found under-classification probabilities ranging from 4.30 to 13.24 %, with the estimated under-classification rate also being higher for chemicals classified based on persistence only (Haseman et al. 2005).
The under-prediction rate for the Cat 1 subgroup that was classified based on persistence of effects only increased to 22%% when only liquids were considered.
Finally, chemicals that did not show sufficiently severe ocular lesions (COMaj < 3, IRMaj ≤ 1.5 and CO ≠ 4) but that were classified Cat 1 based on persistence of effects (Persistence only) were separated and further subdivided into those that showed persistence of CO and those that showed persistence of CR, CC and/or IR, but not CO (No CO).
For example, 65%% of the Cat 1 chemicals in the NCD were classified based on persistence of effects only, whereas this was 35%% for the RCD.
The only other study that has investigated readmissions based on WRF persistence found no significant difference by adjusted analyses for either WRFt or WRFp in 90-day all-cause readmission or HF-related readmission.
The real-world persistence alternative assumed all patients were treated by weekly or monthly bisphosphonates and was based on current persistence rates from observational studies.
