Ideally, we would like to see 100% of pediatric interventions based on pediatric studies.
Clinical management was based on pediatric history and physical examination.
Because the population model was based on pediatric patients with mild hypothermia during CPB, this dosing recommendation may not apply to conditions of moderate to deep hypothermia during CPB as low body temperature has been reported to be a factor reducing CL during CPB [ 12, 13].
Our study has revealed that a great majority of interventions in the PED are based on pediatric studies (83.7%).
Mortality was tracked for 28 days after enrollment, and organ-failure data were based on pediatric-specific criteria [ 19].
Traditional methods for estimating pediatric dosages include dosing algorithms such as Clark's rule (i.e., based on body weight (BW)), Young's rule (i.e., based on age), body surface area-based dosing (i.e., same mg/m), and allometry (i.e., based on BW).
Therefore, dosing regimens should be based on actual body weight.
¤Should be calculated based on actual body weight.
Anaesthetic concentrations were based on predicted body weight.
The dose of heparin is based on actual body weight.
