In combination with advanced computational methods, such as molecular identification based on pattern recognition, it is a promising approach to comprehensively map macromolecular architecture inside organelles and cells and to visualize macromolecules at work in their natural environment.
Since the model is based on direct pattern identification within a network, it provides an efficient method to identify functional interaction or crosstalk between stimulation pathways (also referred to as 'structures') which can be used to define constraints for more detailed network reconstruction.
Recently, Yates et al. [ 34] developed the ADRTrace system based on lexicons, pattern identification and a synonym set including variations of medical terms in order to identify 'expected' and 'unexpected' ADRs.
We recently reported the identification of 17 breast cancer subgroups based on patterns of 18 different oncogene and tumor suppressor pathway activities [ 14].
Selection of indicators will likely vary among countries based on patterns of pharmaceutical usage, DWTP treatment levels, and analytical capability; a relatively large-scale initial survey of pharmaceutical levels and patterns is therefore still needed for indicator identification.
Our definition is based on the identification of frequent patterns in the content, using data mining techniques [12].
However, when using both of the above approaches we found that left right femur symmetry was increased after adjusting for subject positioning during image acquisition based on the identification of oppositional asymmetric patterns of shape variation.
Based on the identification of five TCM patterns, we expanded the sample volume to 2,050 and extended the phenotypes from 21 to 107.
The ictal periods were determined based on the identification of typical seizure patterns preceding clinically manifest seizures in intracranial recordings by visual inspection of experienced epileptologists.
In this study integrative analysis of miRNA and mRNA profiles based on the identification of correlating expression patterns revealed potential functional relationships and pathways involved in the cellular treatment response [ 13].
