Sentence examples for based on pathways that from inspiring English sources

In addition, we looked for further interactions based on pathways that are known or expected to be involved in insulin resistance.

These issues have prompted a renewed focus on developing targeted therapy based on pathways that are altered during the pathogenesis of lung cancer.

However, it is not a straightforward task to construct a prognostic signature based on pathways that are composed of overlapping sets of genes.

The ability to define these circuitries biologically, parse them out at the transcriptional level, and assess their prognostic associations will allow the identification of tumor subtypes based on pathway activities that not only predict for tumor behaviors but also explain them.

As highlighted by the proposed Health Bill for 2011, the desire to move to outcome-based payments for healthcare based on patient pathways that are informed by clinical and financial best practice has not waned.

Candidate gene selection was primarily based on biological pathways that are predicted to be involved in ovarian carcinogenesis.

Beyond the survival differences between clusters, a Cox proportional-hazards model also gave prognostic profiles based on the pathways that were, in addition to that given by stage and age, indicating the existence of further subgroups not captured by the hierarchical clustering.

This capacity is based on molecular pathways that lead to control of gene expression and induction of specific phenotypes in the absence of DNA sequence modification [ 1].

In the last few years, efforts have begun to characterize tumors based on molecular pathways that will serve as targets for new, non-toxic chemotherapeutic agents.

Interestingly, our unbiased scan based on pathways collected in Biocarta also indicated that the overall distribution for all the SNPs within the downstream genes targeted by Gleevec appears to be significantly different from the null distribution.

Based on pathway enrichment analysis, we found that most of the pathways that revealed a positive monotone trend were involved in host immunity.