Sentence examples for based on pathway and from inspiring English sources

It is encouraging that the biology is reflected in this grouping, since the modules align with functional associations based on pathway and GO term enrichment analyses (Table 3 and Additional file 1).

A desired application of these results involves eventual clinical uses which will be capable of using off the shelf enrichment algorithms for genes (e.g. GSEA, [ 16]) to automatically infer phenotype differences based on pathway (and other gene set) -level feature vectors.

This different specification is not irrelevant as many genome analysis methods are based on pathways and are therefore affected by how these are defined (see for instance [ 20] in this supplement).

Compared with the approach of Ramos et al. (2008) which creates an in silico annotation network based on pathways and protein interaction data and maps the gene list of interest afterwards, ClueGO generates a dynamical network structure by already initially considering the gene lists of interest.

This study demonstrated that the carbon skeleton of FGFC1 was synthesized in a mixed biosynthetic mode based on pathway inhibitor and precursor regulation; the process involves the shikimate and mevalonate pathways.

For CD, Wang et al. [ 14] used a different prioritizing criterion based on pathway analysis and they uncovered a significant association between susceptibility to CD and the IL-12/IL-23 IL-12/IL-23 IL-12/IL-23enes.

This network could reveal potentially novel disease relationships that are solely based on pathway association and cannot be readily identified through literature search.

Based on pathway analysis, MFA, and thermodynamic properties, we identified several promising pathways that can be engineered into a host organism to accomplish bioremediation.

Based on pathway aberration profiles of colon and ovarian cancers, we identified two additional aggressive (p <0.05) subgroups.

The software tool CARMEN supports the in silico reconstruction and visualization of automatically derived metabolic networks based on pathway information from the KEGG database and user-defined SBML templates.

Conceivably, Cmap could be used in conjunction with preexisting gene classifiers to make predictions on field samples with unknown exposures, validate candidate gene classifiers using pre-established reference GEPs, categorize environmental stressors into a more manageable number of chemical classes based on pathways affected, and link chemical stressors to their apical biological endpoints.