Sentence examples for based on pathway from inspiring English sources

For example, 36%and47%7% of the metabolic pathways in yeast are confined within only one or two compartments, respectively (based on pathway annotation data in the model of (Duarte et al., 2004).

Functional association analysis performed by ToppCluster based on pathway networks showing enriched terms from Gene Ontology and pathways.

This study demonstrated that the carbon skeleton of FGFC1 was synthesized in a mixed biosynthetic mode based on pathway inhibitor and precursor regulation; the process involves the shikimate and mevalonate pathways.

An in-depth analysis of 288 NDD genes shows there is highly significant protein protein interaction (PPI) network connectivity, and functionally distinct PPI subnetworks based on pathway enrichment, single-cell RNA-seq cell types, and multi-region developmental brain RNA-seq.

Clustering tumours based on pathway signatures further defines prognosis in respective patient subsets, demonstrating that patterns of oncogenic pathway deregulation underlie the development of the oncogenic phenotype and reflect the biology and outcome of specific cancers.

This filtering may be achieved either by ranking as has been previously discussed, clustering of results based on pathway similarity or overlap [68], allowing the user to exclude pathways based on the presence or absence of specific intermediates that the user chooses to avoid, or some mixture of all of these.

Several modeling approaches to the progression and recurrence of cancer have been recently proposed based on pathway-based signatures [10], [11], [12].

We predict that two example biosynthetic pathways have distinct optimal organization strategies that vary based on pathway-dependent and cell-extrinsic factors.

Some of them classify tumor samples based on pathway-level measurements [ 30]; many of them, such as PWEA [ 31] and GSEA [ 32] identify perturbed pathways between two distinct phenotypes (e.g., tumor vs. normal) using expression data [ 28].

At least in AD, it has been challenging to define the nature of the 'immune-system dysregulation' based on pathway-type analyses; the overlap between the SAPS/SMS and biomarkers of AD suggest that the 'immune-system dysregulation' may, in fact, reflect senescence [ 71]. aB, brain; C, cerebrospinal fluid; P, plasma.

For the KEGG metabolic pathway and COG functional category information, user can retrieve interest genes based on pathway/COG ID or description.