FENSAM is based on pathology response rate, clinical indicators, and pathologic markers (Mittendorf et al, 2011; Yi et al, 2011) and is reliable and easy to use.
In ALS and Huntington disease, the picture is less clear as the majority of studies were hospital-based, retrospective in nature, with a final diagnosis not always based on pathology or genetics and the risk factors not properly assessed; thus making comparisons and inferences inaccurate.
Eventually a classification based on the reason the patient consulted emerged to replace that based on pathology defined disease.
These patients were all found to harbor spinal column tumors involving the posterolateral elements that, based on pathology, would benefit from en bloc resection.
One hundred seventy-seven patients were found to have appendicitis based on pathology.
Morbidity rates differed based on pathology, with patients undergoing treatment for kyphosis and spondylolisthesis having higher overall rates of morbidity (14.7% and 9.6%, respectively).
RESULTS: Among 269 biopsy procedures, 257 (95.5%) produced a diagnostic tissue specimen based on pathology reports and were deemed successful procedures.
Based on pathology, the rectal cancer was diagnosed as moderately differentiated adenocarcinoma, and this adenocarcinoma had lymph node metastasis (yp T3N2aM1b).
Cases were classified according to the WHO system based on pathology reports and 20% of cases were re-reviewed by a team of lymphoma pathologists.
