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The example of heterologous sequence elimination through deleting unpaired loops was based on pairing between homologous chromosomes.
miRNAs modulate gene expression by inhibiting mRNA translation or regulating mRNA degradation at the post-transcriptional level based on pairing between the 5' end of the miRNA (i.e., 2-8 nthethe"seed"region) and the 3' untranslated regions (3' UTR) of target mRNAs [ 1, 38– 40].
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Additional file 6: Differential expression of miRNAs during Atlantic cod embryonic and larval development under four temperature regimes, based on pair-wise comparison between treatments.
NJ trees were based on pair wise distances between amino acid sequences using the programs NEIGHBOR and PROTDIST (Dayhoff option) of the PHYLIP 3.6 package [ 42].
NJ trees were based on pair wise distances between amino acid sequences using the programs NEIGHBOR and PROTDIST (Dayhoff option) of the PHYLIP 3.6 package [ 91].
Fixation indices (FST) [ 89] based on pair-wise distance between individuals (number of shared peaks in AFLP profiles) were calculated in ARLEQUIN v3.01 [ 90] with significance set to P < 0.05 (tested by 50,172 permutations among groups).
Hence, some patristic distances from ML trees are greater than the equivalent estimates of genetic distance, when the genetic distances are based on pair-wise comparisons between the raw sequences.
The phylogenetic analysis was based on pair-wise sequence identity between precursors, and the significance of the sequence identity cutoff was evaluated with a z-score.
The BLAST matrix, based on pair-wise gene comparisons between the genomes of all microbes support the present Brucella taxonomy remarkably well suggesting a correlation between marker gene based phylogeny and the proteomes in genus Brucella.
c P-values based on paired Student t-tests for comparison of means between placebo-treated and adalimumab-treated patients.
Evolutionary rates such as Ka, Ks, and Ka/Ks were estimated based on orthologous pairs between human and mouse genes (Methods).
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