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5 Serogroup B vaccines based on outer membrane vesicles have been used to control serogroup B outbreaks.
Another experimental sub-unit vaccine, based on outer membrane antigens, was developed by the API for Siberia and the Far East, Irkutsk.
All strains isolated from the nasopharynx of healthy cattle and representing at least two epidemiological clones based on outer membrane protein (OMP) typing (OMP types 1.2 and 1.4) contained three perfect repeat units per promoter (Table 4).
Experimental vaccines have been based on outer membrane (OM) 'blebs' released from the surface of meningococci during growth and from which toxic lipopolysaccharide has been selectively removed by extraction with deoxycholate detergent.
It was more primitive than other eubacteria in probably lacking lipopolysaccharide, hopanoids, cytochrome b, catalase, the HslV ring protease homologue of proteasomes, spores, the machinery based on outer membrane (OM) protein Omp85 used by more advanced negibacteria to insert outer membrane proteins, type I, type II, and type III secretion mechanisms, and TonB-energized OM import systems.
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To address this question we separated MCF-7 cells into two subpopulations based on outer membrane-exposed mER-α levels and confirmed their differential mER-α expression by several methods.
cc2d2a−/− fish based on outer segment length and rhodopsin mislocalization.
- Development of serogroup B capsular polysaccharide-based vaccines has not been successful, and MnB vaccines based on the outer membrane protein porin A (PorA) have been effective only against epidemic MnB strains., No broadly protective vaccine is currently licensed for the prevention of IMBD.
A vaccine based on native outer membrane vesicles (NOMV) that has potential to provide safe, broad based protection against group B strains of Neisseria meningitidis has been developed.
This difference can be explained because the antibodies are usually present long after an infection starts [ 10, 41] and because the commercial ELISA test used in the present study detects antibodies based on the outer membrane proteins and thus detects infections with all pathogenic Yersinia.
Further classification of N. meningitidis is based on major outer-membrane porins into serotypes and serosubtypes as well as LPS (lipopolysaccharide) into immunotypes [ 3].
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based on biomimetic membrane
based on specific membrane
based on integral membrane
based on outer ring
based on cytoplasmic membrane
based on certain membrane
based on outer synchronization
based on green membrane
based on recombinant membrane
based on outer segment
based on quantitative membrane
based on total membrane
based on cellular membrane
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