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If such a distribution is characteristic for an unknown class of ncRNAs, the clustering based on our score should be able to detect it.
Overall, we found a significant but weak positive association between the original ranking and a ranking based on our score (correlation = 0.12, p<0.001).
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Based on our scoring function (see Methods) we provide a ranked list of potential PPI drug targets (Table 2).
Non-coding sequences also appear to be more similar to its neighbors than expected by chance based on our scoring scheme.
Based on our scoring criteria, 13 of 27 (48.1 %) samples that had adequate tissue for analysis were considered positive.
The procedure corrects for single insertion and deletion errors to produce the best scoring full alignment based on our scoring criteria for the region of overlap.
Thus, categorization based on our scoring system would permit a longer time interval between the initiation of these two treatments for such patients.
Hence, myotonia is fully penetrant in draggen mutants, including females that have never shown a dragging episode based on our scoring system.
To select proteins with a high likelihood as candidate effectors we focused on tribes that ranked highly based on our scoring system, are highly expressed and enriched in haustoria, and display sequence polymorphisms between isolates.
Although DALI considers all the tools in its library as DAs, based on our scoring using the IPDAS there is large variation in quality across the included DAs whether they are listed in DALI or not.
We determined students' ability to identify the five moves of SAM (motive, objective, main conclusion, implication, and counterargument) by attributing points to their answers, based on our scoring model.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com