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We also retrieved KO data from KEGG and then classified enzymes from non-enzymes based on our pathway mapping results.
This protein is involved in cytoskeletal remodelling, which might also be an involvement of the NMDA receptor under physiological conditions, however based on our pathway model this would imply that apoptosis is to some extent inhibited, whereas necrosis is not.
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However, based on our results, a pathway to bone formation through chondrocytes might be possible during development of vertebral fusions.
Based on our simulation, this pathway is thought to be the only route redirecting carbon flux from xylose to PPP in the wild-type cell.
Based on our findings and pathway analysis, we hypothesize that elevated levels of miR-433 might be a signature of the fate switching of striatal precursors towards proliferation and lineage commitment under the influence of IGF-1IGF-1
We have drawn pathways based on our desire to model pathways active in a human macrophage and therefore all components have been depicted using standard human gene nomenclature (HGNC).
Based on our literature review, a pathway of "astrocyte-IL-1β-NMDAR-Fos" may exist.
Based on our proteomic findings and pathway analysis predictions, we wanted to investigate if albumin-bound proteomic profiles were correlated to plasma HDL and cholesterol levels.
This was based on our previously described tru pathway-based expression system.
Pathways were built using Ingenuity Pathways Analysis, as described in Methods section, using both pre-defined 'canonical pathways' and custom-built pathways based on our own queries for genes/pathways not included in the canonical pathways.
Both pre-defined 'canonical pathways' and custom-built pathways based on our own queries for genes/pathways not included in the canonical pathways were used to establish these networks.
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