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Based on our conclusion that Jak2 binding is sufficient to inhibit GHR endocytosis, we hypothesised that Jak2 must leave the GHR before the endocytosis machinery, including SCF βTrCP) and clathrin, can proceed [16].
First, based on our conclusion that most cis-acting QTL are mildly deleterious, we expect that among any pairwise comparison of strains, fewer cis-acting QTL would be present than predicted under neutrality.
Mitotic recombination might be a driving force in MAP carcinogenesis, based on our conclusion that the LOH in MAP carcinomas mainly comprise copy neutral LOH.
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Based on our conclusions, the present work provides a detailed model for the phosphorus dynamics which is connected to a two-dimensional heterogeneous reactor model.
Based on our conclusions, if the state intends to secure some territories as areas of transformative adaptation to climate change, the areas should comprise reticular territories made up of stock routes and numerous pasture areas rather than disconnected state ranches.
Based on our conclusions we recommend customizing the design of climate research programmes and projects towards the needs of the specific societal benefits they aim to generate and reconsidering the emphasis on formal involvement of societal actors in funding procedures.
Based on our conclusions from the k252a analysis, we performed single SILAC experiments using soluble competitor concentrations of 10x and 100x and applied our statistical model to assess the probability that each detectable protein was bound by SB-202190 given these 2 SILAC ratios.
Based on our conclusions, we formulated a modified DTC management algorithm that includes highly sensitive Tg assays and is shown in Fig. 1.
Based on our conclusions, we make three recommendations: firstly, the design, implementation and management of service integration should engage with and account for local variability and the active influence of nurses and patients, through closer, more dynamic approaches to management.
For the work of [ 21] as well as the present investigation, we decided to pool the tinnitus subjects based on our previous conclusion that a distinction between tinnitus with and without hearing loss is probably not meaningful [ 17, 52].
Based on our findings, the conclusion is that personalized elderly care assistance emerges as a socio-technical construction of social media.
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