Node N2 uses a support vector machine to separate bidirectional from unbounded promoters based on two features the presence of CpG islands and RP score, while node N3 uses a decision tree to separate enhancers from non-promoters based on one feature RP score (it turns out that these two classes cannot be distinguished based on the presence of CpG islands, so this feature would not be helpful).
We observed that a proportion of patients (about 12%) had fluctuating Villalta scores beyond 6 months after the acute event of DVT. 8 Assigning the diagnosis based on one single score ≥5 would therefore lead to misclassification and overestimation of the PTS incidence.
Although the consensus is to diagnose PTS at the 6-month visit or later based on one single Villalta score ≥5, 24 we modelled this study after the preceding management study in which two consecutive Villalta scores ≥5 were needed for the diagnosis of PTS.
Several other highly ranked genes have achieved their rank based on one outlier z-score.
In 58% of the latter, the score was based on one to two available thoracic VCs scores, and the remaining two to three were imputed because they were missing.
In 58% of those, in which the RASSS was calculated, the score was based on one or two available thoracic VC scores and the remaining two to three needed imputation because they were missing, so were in fact non-informative.
However, a dichotomous measure of improvement incorporating CGI, ABC-I and Modified Overt Aggression Scale [ 53] scores, based on one of the studies [ 40] suggested that more children showed an improvement in challenging behaviour following treatment with valproate than those given placebo (RR = 0.41, CI 0.21 to 0.80, p = 0.009).
The CCI score is based on one year mortality data from internal medicine patients admitted to an inpatient setting and is the most widely used comorbidity index in oncology.
Since validated cut-off points for "casesness" among YSR-syndromes do not exist for Nicaragua or Cambodia, the YSR-syndromes were entered as continuous variables in the logistic regression analyses, i.e. ORs were calculated based on one point increment on YSR-syndrome scores.
The reliability for a score was 0.71 based on one rater.
