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Small molecule-based methods have been developed based on observation that treatment of cells with DNA methyltransferase 1 (Dnmt1) inhibitors accelerates reprogramming (Mikkelsen et al, 2008).
The procedure was the kind of analysis based on observation that doctors do every day, the clinic maintained.
However, Ex-Ambassador Smith has returned from Moscow with the news that nonagenarians are common in the Dzhugashvili family and with the opinion, based on observation, that the Generalissimo is feeling tiptop and has many years or rich, full living ahead of him.
A unified model of dynamin architecture is presented here, based on observation that the basic dynamin fold is conserved across evolutionary kingdoms.
Recently, Guikema et al have suggested that both APEs are involved in CSR, based on observation that CSR and DSBs in Sμ are moderately reduced in mice deficient in APE2 or haploinsufficient for APE1 [18].
We did not fully characterize the T191I NA mutation that emerged in our 2nd selection experiments, but based on observation that this amino acid is located far from the NA active site we expect that this mutation likely affects NA activity by reducing NA incorporation into virions, rather than directly altering enzymatic activity.
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This claim is based on observations that show that the proposed protocol has such strengths as light computational load, efficient storage management, and dependability.
One version was based on observations that were made on days when neither partner had an infant under the age of 100 days.
However, models are highly uncertain because they are based on observations that are geographically and temporally distinct from the population to which they are applied.
The first author (LB) conducted 76 hours of participant observation at ED1 and wrote extensive field notes based on observations that took place both before and after focus group interviews and covered both daytime and nighttime shifts.
Based on observations that released airbags are consistently observed in crashed cars, but never in intact cars, the airbag became the suspect and possible initiating cause of the accidents.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com