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These two conditions might be reported as ex-post justifications for the performed CD, rather than being based on objective clinical assessment [ 11, 12].
The diagnosis and the source of blood-stream infection were determined by the physician in charge and a specifically trained nurse, and were based on objective clinical evidence, microbiological data, clinical judgment and the definitions proposed by CDC.
Risk scoring based on objective clinical parameters indicated that patients with a high score had a significantly shorter OS, and this may help in the process of patient selection for phase I trial entry.
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The use of this score might be helpful for the future as it is based solely on objective clinical parameters.
This diagnosis and criteria used for volume assessment was based on objective data and the clinical assessment by the treating ICU physician, as heart rate, blood pressure, respiratory rate, as well as invasive monitoring with CVP measurements.
Such an approach to disease stratification means that we are now in a position to redefine subtypes of disease based on objective laboratory parameters, independent of clinical manifestations.
These findings are important because evidence-based clinical practice mandates that clinical advice and decision-making be based on objective measures of risk.
The clinical differentiation of PARTNER high-risk operable from inoperable patients based on objective parameters is not straightforward and essentially based on the clinical feeling of the physicians involved.
A clinical algorithm for asthma management based on objective measures and asthma symptoms could potentially reduce asthma exacerbations during pregnancy.
It demonstrated discriminative ability based on objective geriatric assessment measures, but additional investigations on use for clinical decision-making are warranted.
In light of these considerations, we propose here a new algorithm for deciding the clinical use of EGFR-targeted monoclonal antibodies that is based on objective response rates (Figures 5 and 6).
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