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GHs are assigned to 112 families (http://afmb.cnrs-mrs.fr/CAZY/) based on nucleotide or amino acid sequence.

To our knowledge, there is no clear definition of a nebovirus genotype based on nucleotide or amino acid sequence identities.

There is no consensus on the criteria to identify alleles based on nucleotide or protein sequences similarity.

However, no strong support in favor of this relationship is found, whether reconstructions are based on nucleotide or protein sequences (PPDNA = 0.57; PPPROTEIN = 0.75).

Finally, ASGARD users may search all transcriptome sequences based on nucleotide or protein similarity to nr sequences using the embedded NCBI BLAST module.

Similar(55)

Blastn and Blastp analysis based on nucleotide sequence or the corresponding amino acid sequence was performed in NCBI against Zea mays, rice or Arabidopsis.

Estimations of Maximum Likelihood (ML) phylogeny based on nucleotide sequences or amino acid sequences and an estimation of a Bayesian phylogeny resulted in a phylogenetic tree with a robust separation of 'long-form' and 'short form' pirs.

Our findings of lower levels of diversity in males and on the Z-chromosome relative to the autosomes are concordant with results of previous studies based on nucleotide sequences or microsatellite variation in a wide range of species including the collared flycatcher [ 22], chicken [ 23], human [ 24, 25], house mice [ 26] and Drosophila [ 27, 28].

Other approaches to quantify the extent of LGT are based on nucleotide composition or codon usage patterns (Mrázek and Karlin 1999; Nakamura et al. 2004; Kechris et al. 2006), inferred gene gain and loss events (Snel et al. 2002; Kunin and Ouzounis 2003; Hao and Golding 2006; Iwasaki and Takagi 2009), and assumptions about ancestral genome sizes (Dagan and Martin 2007).

A total of 187 metagenomic clones identified as being Syn OS-A or Syn OS-B'-like (based on nucleotide identity of either the sequence or its clone-mate to the genomes) were found to contain Type I (43 clones), Type II (139 clones) or Type III (5 clones) CRISPRs.

The fundamental disagreement between phylogenies based on nucleotide (fig. 1 A) or amino acid (fig. 1 B) sequence data for mt proteins stems from the fact that none of the available models for sequence evolution adequately account for the observed data (Kitahara et al. 2014).

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