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At least six major HCV genotypes and more than 50 subtypes have been described based on nucleotide diversity of the core, E1\E2, and NS5 regions [3], [4], [5].
This is based on nucleotide diversity combined with a standard deviation.
Finally, the branching patterns and estimates based on nucleotide diversity indicate a population expansion after the Last Glacial Maximum.
Whole-genome sequences were aligned and pairwise distances between genomes, based on nucleotide diversity levels, were compared within and between groups of carriage and virulent strains.
Finally, we tested if the pmt allele frequency distribution, based on nucleotide diversity measures, deviated from neutrality in a tolerant and sensitive population.
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This indicated that the type I pili in pneumococci circulating in Malawi were genetically closely related to those identified in the global Pneumococcal Molecular Epidemiology Network collection, previously classified into 3 main clades based on nucleotide sequence diversity (12).
It is interesting that natural populations in China have relatively high genetic diversity based on the nucleotide diversity and haplotype diversity (Table 1).
For each island, we calculated the number of haplotypes based on nucleotide substitutions (h), number of private haplotypes (ph) and haplotypic diversity (H) [41].
These analyses were based on nucleotide sequences.
Based on average nucleotide diversity, long term effective population sizes were estimated to range between 18,000 (for μ = 10-8 per site per generation) and 230,000 (for μ = 10-9 per site per generation) across four collections (Table 1).
Finally, it is possible that the N e estimates based on nuclear nucleotide diversity data do not accurately reflect the current population-genetic environments experienced by these two intraspecific clades.
More suggestions(16)
based on spatial diversity
based on genetic diversity
based on nucleotide sequence
based on nucleotide conservation
based on nucleotide spacing
based on nucleotide identity
based on haplotype diversity
based on nucleotide coding
based on nucleotide frequency
based on allelic diversity
based on phylogenetic diversity
based on genomic diversity
based on nucleotide complementarity
based on nucleotide sequencing
based on different diversity
based on ethnic diversity
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