Sentence examples for based on normal keratinocytes from inspiring English sources
These data suggest that models based on normal keratinocytes atop a fibroblast-containing connective tissue will significantly aid in dissecting the molecular pathogenesis of oral candidiasis.
The aim of the present study was to clarify the additional processed forms found in PPP vesicles and their physiological effects on normal keratinocytes and sweat gland cells.
In conclusion, the combination of TNF-α and histamine has a profound growth-inhibitory and cytolytic effect on normal keratinocytes.
The effects of moderate and high doses of ionizing radiation on human keratinocytes have been extensively investigated, using large scale genomic approaches [ 2- 4]; the effects of low-dose radiation on normal keratinocytes, on the other hand, remain largely unknown.
Therefore, of interest is the previous finding on normal keratinocytes that the treatment of keratinocytes with histamine and TNF-α leads to increased ICAM-1 expression [ 14] and also to increased cytolysis.
Two of the tumour-derived cell lines and the two erythroplakia-derived cell strains expressed EGFR at levels similar to that detected on normal keratinocytes in tissue culture.
There was lower ROS produced at the more selective dose of 3 µM that had a minimal growth inhibitory effect on normal keratinocytes.
When acting together, histamine and TNF-α have shown synergism in the induction of ICAM-1 on normal keratinocytes, an induction which probably requires H2-receptors [ 14].
DHA is just as specific as EPA in inducing ERK1/2 phosphorylation in SCC keratinocytes relative to their normal counterparts, yet is much less specific at inhibiting their growth, especially at 5 µM, where it has a considerable effect on normal keratinocytes.
