Sentence examples for based on mutations in from inspiring English sources

The limitation of HA degradation may be based on mutations in one or several of the genes coding for the HA degrading enzymes.

Many animal models of colorectal cancer are based on mutations in the Apc (adenomatous polyposis coli) gene, which is mutated in over 80% of colon cancers in humans (Fearnhead et al., 2001).

Active Motif Finder (AMF) is a novel algorithmic tool, designed based on mutations in DNA sequences.

Interestingly, the lethality score that was only based on mutations in expressed regions could not distinguish normally and abnormally proliferating old SCCs.

Genomic and proteomic approaches have presently identified eight different forms of NCL (namely, CLN1 through CLN8) based on mutations in specific genes.

The HHT analysis method can identify reflections from the long protruding end of the bolt and multiple reflections from grouting defects based on mutations in the instantaneous frequency, which makes weak reflections more noticeable.

Such trees were drawn up by Dr. Wallace and others, based on mitochondrial DNA, and more recently by Dr. Underhill and his colleagues, based on mutations they found in the Y chromosome.

The pathology characteristics based on mutation status are presented in Table 3. Table 4 shows a more detailed breakdown of grade 3 tumours.

Tran, E. et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.

Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, Wunderlich JR, Somerville RP, Hogan K, Hinrichs CS, Parkhurst MR, Yang JC, Rosenberg SA (2014) Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.

Fearon and Vogelstein (1990) first proposed a temporal ordering of mutations based on the mutations in colorectal tumors from different stages.