Sentence examples for based on mutations from inspiring English sources

The limitation of HA degradation may be based on mutations in one or several of the genes coding for the HA degrading enzymes.

A most interesting example of this approach was provided by a study on EGFR-based Gefitinib resistance, which demonstrated resistance based on mutations that were not clonal, but could be revealed by application of the 454 Sequencing System (454 Life Sciences, Branford, CT, USA; Thomas et al, 2005).

Many animal models of colorectal cancer are based on mutations in the Apc (adenomatous polyposis coli) gene, which is mutated in over 80% of colon cancers in humans (Fearnhead et al., 2001).

Personalization was based on mutations and analyses of the transcriptomes and immunopeptidomes of the individual tumours.

Active Motif Finder (AMF) is a novel algorithmic tool, designed based on mutations in DNA sequences.

Interestingly, the lethality score that was only based on mutations in expressed regions could not distinguish normally and abnormally proliferating old SCCs.

Recently, fault-based criteria, such as that ones based on mutation testing, have been investigated for variability test using the FM (Ferreira et al. 2013; Henard et al. 2013a).

Tran, E. et al. Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.

Surface residues are colored based on mutation frequency of deleterious missense mutations at the time of analysis in cBioPortal, for residue positions 758–1335.

The problem seems to be that JavaScript developers want to use functional programming techniques like laziness and immutability but have to interface with a DOM specification that is based on mutation.

Tran E, Turcotte S, Gros A, Robbins PF, Lu YC, Dudley ME, Wunderlich JR, Somerville RP, Hogan K, Hinrichs CS, Parkhurst MR, Yang JC, Rosenberg SA (2014) Cancer immunotherapy based on mutation-specific CD4+ T cells in a patient with epithelial cancer.