Sentence examples for based on mutational analyses from inspiring English sources

Based on mutational analyses and NMR data, we derive a structure of the complex showing that the PWWP domain is bound to H3K36me nucleosomes through simultaneous interactions with both methylated histone tail and nucleosomal DNA.

Putative functional effects of mutations are based on mutational patterns.

Patients were then stratified in three equally large groups based on mutational burden.

PDAC can be classified based on mutational subtypes and 18gene alterations.

Davies, H. R. et al. HRDetect is a predictor of BRCA1 and BRCA2 deficiency based on mutational signatures.

Unbiased clustering, based on mutational context, revealed clinically relevant subgroups regardless of the tumors' tissue of origin, highlighting similarities in evolutionary dynamics leading to hypermutation.

These studies suggested several hypotheses based on mutational biases or selective constraints.

No differences in the involvement of oncogenic pathways were noted between the two sites, based on mutational profiles.

Based on the mutational analyses and the EMSA experiments, we now propose that the AGCA sequence at −45 to −42 is the site with which the complex of αCTD with oxidized Spx directly interacts.

Based on these analyses, we set the threshold to find mutational enrichment in the HML subset as twice the baseline difference between HMLs and LMLs.

All based on group analyses.