Sentence examples for based on mutation testing from inspiring English sources
Recently, fault-based criteria, such as that ones based on mutation testing, have been investigated for variability test using the FM (Ferreira et al. 2013; Henard et al. 2013a).
A study was eligible for the meta-analysis if it was based on mutation testing of a series of index cases diagnosed with either breast (male or female) or epithelial ovarian cancer and who were unselected for family history of cancer.
Due to tumor heterogeneity and the large amount of genes found to be mutated in CRC [ 99], a screening stool test solely based on mutation biomarkers would require testing a large number of genes.
Personalization was based on mutations and analyses of the transcriptomes and immunopeptidomes of the individual tumours.
Apart from our contributions, some other researchers have been investigating fault based-testing for AO programs, mainly focusing on mutation testing.
We further corrected the mutation carrier probabilities based on supplementary mutation carrier testing of relevant members in some of the families.
In the past decade, researchers have developed prenatal tests for gender and Rh blood group based on testing for mutations in fragments of fetal DNA circulating in the blood of pregnant women (Science, 2 September 2005, p. 1476).
Other labs also identified a grinch phenotype (Lyle Zimmerman, Robert Grainger, personal communication), which based on complementation testing were mutations at the same loci and at the time thought to be identical alleles.
Most of these assays were based on bacterial reverse mutation tests or on somatic cells, such as primary and permanent cell lines including transgenic reporter cell lines, but did not rely on embryonic or germ cells (Brown et al. 1995; reviewed in Spielmann 1998; Spielmann 2005).
On the other hand, because we identify mutation clusters purely based on nonsynonymous mutations, post-hoc testing for elevated dN/dS in cluster regions suffers from ascertainment bias.
