Sentence examples for based on mutation analysis from inspiring English sources
No patient selection based on mutation analysis was performed at the time of approval and all eligible NSCLC patients were treated with erlotinib [14].
Flowering time is a well studied trait in Arabidopsis, and numerous flowering time genes have been identified (cloned) in Arabidopsis, based on mutation analysis [22] [24], but that the relationship between these genes and the QTL underlying variation in mapping populations derived from accession crosses is unclear.
The next phase of reports were of studies based on mutation analysis.
The identified variants were normalized relative to the base pairs screened and individuals assessed and our case-control results were compared to three large studies that have established an approximate frequency based on mutation analysis of germline DNA of healthy individuals representative of the natural rate of mutation.
A more accurate percentage for the closed state can be determined based on mutation and energy analysis.
Although within-site sample sizes are low, it is worth noting that the TreeSAAP analysis is not based on mutation frequencies within populations, but upon the sequences themselves, and so is less affected by sampling strategy than approaches such as dN:dS ratios [ 56].
Here, we describe the application of ancestral libraries libraries based on mutations predicted by phylogenetic analysis and ancestral inference.
This study was carried out based on the mutation analysis in P. falciparum chloroquine resistant transporter (pfcrt) and P. falciparum multidrug resistance 1 (pfmdr1) genes.
The microarray detection limit was assessed based on the mutation analysis of two plasmids carrying exon 1 of the gene coding for low-density lipoprotein receptor with two types of mutations (i.e. G>T, G>A).
Based on our mutation analysis, we selected five candidate regulators from three of the four eQTL hotspots for further validation using knock-out experiments (PBF2, SDS24, REI1, RAI1, and KAP114).
Based on this analysis, mutations were classified as nonsense, missense or silent.
