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This has led to the idea that statistical models based on multiple predictors (PSA, age, family history, other markers) might be used to predict biopsy outcomes and hence aid biopsy decisions for individual patients.
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We chose logistic regression, because it will predict the outcome of a binary response variable, that is, whether the response is in or out of a TA category or PS rubric concept, based on multiple predictor variables.
In particular, developing predictors based on multiple SH2 domain probes is likely to improve the discriminating power of SH2 profiling, and is therefore a high priority for future studies.
The results of the linear and mixed models include adjusted approximations of confidence intervals (CIs) and P values based on multiple comparisons (simultaneous inference) of predictors using the "glht" function from the "multcomp" package (Hothorn et al. 2008).
The results of all GLMMs include adjusted approximations of P values based on multiple comparisons (simultaneous inference) of predictors using the glht function from the multcomp package (Hothorn et al. 2008).
A practical implication of this is that we can improve the accuracy of genetic predictors without the need to access large-scale individual-level data sets, and we can potentially combine multiple predictors based on different summary statistics, e.g. combine risk scores based on multiple GWAS studies if a GWAMA is not available.
Result: We developed a new protein domain predictor, ThreaDom, which deduces domain boundary locations based on multiple threading alignments.
"The confirmation is based on multiple intelligence sources".
"However, presidential support is based on multiple influences -- including partisanship.
This assessment is based on multiple lines of evidence.
MPCA establishes multiple dimensions based on multiple factors and then computes multiple linear subspaces representing multiple varying factors.
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