Sentence examples for based on multiple genomes from inspiring English sources

Furthermore, analysis methods based on multiple genomes are essential to properly evaluate the function and meaning of personal genome variants.

One possible explanation for this is the fact that this method was developed for single strain (genome) microarrays whereas the microarray used in this study is based on multiple genomes.

Accurate analysis of the repertoire of such elements in a given population based on multiple genome profiling approaches could reveal significant aspects of ongoing evolution (and transmission) and the available magnitude of genetic diversity among the strains could thus be unraveled.

To identify TFBSs in the long non-coding regions of higher eukaryotes, several methods based on multiple genome alignments were developed [ 24, 25].

A key idea underlying chromatin state analysis is to computationally identify the number and composition of chromatin states in the genome based on multiple genome-wide profiles of histone modifications and to annotate the genome with these chromatin states.

A previous study based on multiple genome alignments had a comparable precision of 3% and 17% in two ChIP-chip experiments, where the authors selected the predicted CRM regions as probes to make the microarray [ 24].

Combining several in silico features (e.g. conserved and stable secondary structures, GC-content, comparison based on multiple genome alignments) with an in vivo dRNA-seq transcriptome analysis of Aquifex aeolicus, we predict roughly 100 novel ncRNA candidates in this bacterium.

We inferred the divergence times of over 98% of all families of land plants in a single phylogenetic analysis based on multiple genes from two genomes (Additional file 1; TreeBase study ID S11106).

Phylogenies based on 61 protein-coding genes (Figs. 2, 3) generally agree with several recent studies based on multiple genes or complete chloroplast genomes [ 37- 39].

The agreement between DdDp and complete genomes corresponded to the results of a 46-taxon composite topology based on multiple genes [16].

Contact: [email protected] Genomic analysis based on multiple species' genomes and gene interaction networks generated by high-throughput technologies is making very large gene set analysis commonplace.