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However, more rationale approaches based on molecular studies would help improving the outcome of these patients.
The literature abounds with evidence, based on molecular studies and immunohistochemistry, implicating the cadherin catenin complex in human disease.
Over the years several smaller taxa were segregated from this taxon, but their separateness was recently questioned based on molecular studies outcomes.
This is particularly important as new biomarkers based on molecular studies of HCC could be incorporated into the model.
Established associations between oncogenic strains of HPV and ACC are based on molecular studies carried out on entire tumour block sections.
Based on molecular studies of 18S rDNA, Whiting et al [ 4] proposed the grouping of Diptera + Strepsiptera under the name Halteria.
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Judicial structural modifications of 5 7-fused ring-expanded nucleosides (RENs), based on molecular modeling studies with one of its known targets, human RNA helicase (hDDX3), led to the lead, novel, 5 7-fuseded tricyclic heterocycle (1).
Design of these compounds was based on molecular modeling studies performed on a related series of molecule in a previous study.
Studies on the substrate scope of this strategy are presented and a catalytic mechanism is proposed based on molecular modelling studies supported by mutagenesis of amino acid residues in the active site.
Thus, the structure and activity relationship is summarized and further discussed based on molecular modeling studies.
Based on molecular modeling studies, macrocyclic inhibitors of phosphatase cdc25B were synthetically derived from steroids.
More suggestions(15)
based on molecular principles
based on molecular markers
based on molecular genetics
based on prior studies
based on molecular functions
based on molecular methods
based on molecular criteria
based on epidemiological studies
based on previous studies
based on solid studies
based on molecular data
based on molecular cytogenetics
based on molecular divergences
based on molecular dynamics
based on molecular properties
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