Sentence examples for based on molecular profiling from inspiring English sources

Clinical trials that are based on molecular profiling, or which include one of the above standard regimens should be encouraged.

Simultaneously, diagnostic criteria based on molecular profiling of early tumors have been proposed.

Currently, based on molecular profiling, breast malignant tumors are classified into five major subtypes: basal-like, two luminal-like, normal-like and epidermal growth factor receptor type 2 (HER2) over-expressing cancers4.

Therapy based on molecular profiling was considered to be effective for a given patient if the ratio exceeded 1.3.

Studies by Perou and colleagues and Sorlie and colleagues have demonstrated that at least five different subtypes can be identified based on molecular profiling [ 1, 2].

Some programs, such as StratomeX, use an unsupervised approach to explore the relationship between clinical parameters and patient stratifications based on molecular profiling [ 24].

The in silico interactomics analyses confirmed that, based on molecular profile of HBEC-EMVs, they could engage in numerous cell-surface interactions with both astrocytes and neurons.

Particularly, the genomic era has been characterized by an exponential increase in the number of putative therapeutic targets by defining subtypes based on molecular profiles [ 3].

Regardless of these clinicopathological features, it is reported that other gene expression profiles based on The Cancer Genome Atlas appear to be similar in patients with KRAS and NRAS mutant mCRC, suggesting that treatment selection based on molecular profile is important [ 30].

Sharing genomic and clinical data is critical to achieve precision medicine (National Research Council 2011), that is, more accurate disease classification based on molecular profiles to enable tailored effective treatments, interventions, and models for prevention.

Furthermore, based on molecular profiles, at least four different subtypes of mammary carcinoma (luminal A, luminal B, human epidermal growth receptor (HER 2-enriched and basal-like) HER 2-enrichedtified [ 3].