Sentence examples for based on molecular profile from inspiring English sources

The in silico interactomics analyses confirmed that, based on molecular profile of HBEC-EMVs, they could engage in numerous cell-surface interactions with both astrocytes and neurons.

Regardless of these clinicopathological features, it is reported that other gene expression profiles based on The Cancer Genome Atlas appear to be similar in patients with KRAS and NRAS mutant mCRC, suggesting that treatment selection based on molecular profile is important [ 30].

Clinical trials that are based on molecular profiling, or which include one of the above standard regimens should be encouraged.

Simultaneously, diagnostic criteria based on molecular profiling of early tumors have been proposed.

Therapy based on molecular profiling was considered to be effective for a given patient if the ratio exceeded 1.3.

Some programs, such as StratomeX, use an unsupervised approach to explore the relationship between clinical parameters and patient stratifications based on molecular profiling [ 24].

Particularly, the genomic era has been characterized by an exponential increase in the number of putative therapeutic targets by defining subtypes based on molecular profiles [ 3].

Studies by Perou and colleagues and Sorlie and colleagues have demonstrated that at least five different subtypes can be identified based on molecular profiling [ 1, 2].

We thereby collected studies from translational systems biology, whereby theoretical predictions helped to design molecular interventions to re-establish impaired cancer cell apoptosis and personalized dosages of chemotherapy based on molecular profiling of apoptosis proteins.

The aim of this study was to establish the molecular characteristics of the two most common cHL subtypes, nodular sclerosis (NS) and mixed cellularity (MC), based on molecular profiling and immunohistochemistry, with special reference to the inflammatory microenvironment.

However, the findings based on molecular profiling have not yet altered diagnosis, and decisions about treatment still rely mostly on histopathological and immunohistochemical techniques which are at best semi-quantitative [ 5, 6].