As the pharmaceutical industry starts developing novel molecules developed based on molecular biology principles and a better understanding of the human genome, it becomes increasingly important to develop early indicators of activity and/or toxicity.
A coarse-grain molecule model based on molecular dynamic simulation principles was developed to understand the formation of the wrinkles, and establish a relationship between GO thickness and the wrinkle wavelength generated.
Protein GO enrichment based on molecular functions.
Developmental biology has evolved from a descriptive science to one based on genetic principles and molecular mechanisms.
Ligand-based methods are based on the molecular similarity principle, which states that molecules with similar structures tend to have similar biological activities (Willett et al. 1998; Bender and Glen 2004).
This paper mainly involves the functions and molecular structure of ideal organic binders for iron ore pelletization based on fundamental principles of molecular design, interface chemistry, polymer science as well as failure model of a binding system.
This exciting field is based on principles of molecular development biology and morphogenesis, gleaned through studies of inductive signals, responding stem cells, and the extracellular matrix scaffolds, which are used to design and construct spare parts to restore function to the human body.
The calculations based on first-principles molecular dynamics showed that this carbon allotrope should be quite stable, but so far no synthetic approach has been found.
The activity coefficients are correlated using a two parameter model based on the principles of molecular thermodynamics.
Modern taxonomic systems, such as the APG which is based on phylogenetic principles using molecular biology, has redistributed many of these genera resulting in the relatively small family that is currently recognised.
