Sentence examples for based on molecular phenotypes from inspiring English sources
Furthermore, breast cancer is a heterogeneous disease with a demonstrated difference in prognosis based on molecular phenotypes.
We also observed that the initial SUV and declining of the SUV differed based on molecular phenotype.
BC can be divided based on molecular criteria into distinct phenotypes: the molecular subtypes are classified by (1) expression of estrogen receptors (ERs) and/or progesterone receptors (PRs), (2) human epidermal receptor 2 (HER2/ERBB2) amplification and (3) a triple negative type (ER-/PR- and normal expression of HER2).
We undertook a search using reverse genetics to try to identify a relationship between genes known to be important in the Fe-uptake pathways based on molecular and biochemical information, and traits or phenotypes associated with QTLs that were likely to be associated with the symptoms of IDC using the Gramene database.
For endometrial cancer, few prognostic markers are available and presently the therapeutic strategy is not based on molecular subclass, despite increasing evidence for this being relevant for clinical phenotypes (Salvesen et al, 2009; Kandoth et al, 2013).
This capacity is based on molecular pathways that lead to control of gene expression and induction of specific phenotypes in the absence of DNA sequence modification [ 1].
Latest studies define endotypes based on molecular and cellular mechanisms, for example defining risk and protective single nucleotide polymorphisms (SNPs) and new immune phenotypes, showing promising results.
Molecular manufacturing will be based on molecular machine systems able to manipulate and assemble molecular components to make larger products.
Giger's team can use Beagle-2 for "rapid, high-throughput image-based phenotyping," mining thousands of images and using machine learning techniques to find features capable of differentiating between invasive and non-invasive cancers, as well as other cancer subtypes based on molecular classifications.
This method can generate hypotheses based on molecular evolution which can then be verified using more direct functional assays and gives researchers an additional computational tool in their search for evolutionary relationships between genotype and phenotype.
